Captured on video by CBS2 New York's news chopper, the incident apparently began around 9 a.m. after the man pulled over and got out of a sedan in the westbound lanes.
The man, clad in tattered clothing, a long, multi-colored scarf covering his head and sunglasses hopped onto the bridge's concrete railing at times -- and even spread his arms and leaned backward.
At another point he dropped to his knees as police kept their distance.
He finally returned to the car and got in. Police then rushed him, pulled him out and got him into handcuffs.
The man was taken to a local hospital for an evaluation. It wasn't immediately known whether he would face criminal charges.
WATCH IT ON VIDEO: Pulaski Skyway Suffers 90 Minute Delay As Police Confront Disturbed Man On Bridge (CBS2)
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